Sinensetin

$34$264

Products Details

Product Description

– Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties.

Web ID

– HY-N0297

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C20H20O7

References

– [1]Kang SI et al. Sinensetin enhances adipogenesis and lipolysis by increasing cyclic adenosine monophosphate levels in 3T3-L1 adipocytes. Biol Pharm Bull. 2015;38(4):552-8.|[2]Shin HS et al. Sinensetin attenuates LPS-induced inflammation by regulating the protein level of IκB-α. Biosci Biotechnol Biochem. 2012;76(4):847-9.|[3]Lam IK et al. In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent. Mol Nutr Food Res. 2012 Jun;56(6):945-56.|[4]Kok-Tong Tan, et al. Sinensetin induces apoptosis and autophagy in the treatment of human T-cell lymphoma. Anticancer Drugs. 2019, 30, 5.|[5]Mirka Laavola, et al. Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. Planta Med. 2012, 78, 8.

CAS Number

– 2306-27-6

Molecular Weight

– 372.37

Compound Purity

– 99.87

SMILES

– O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(OC)=C(OC)C(OC)=C13

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– PGE synthase;TNF Receptor

Pathway

– Apoptosis;Immunology/Inflammation

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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