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Simeprevir
Price range: 48 CAD through 317 CAD
Products Details
Product Description
– Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
Web ID
– T4686
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C38H47N5O7S2
Citations
– 1. Sinokki A, Miinalainen A, Kiander W, et al.PREINCUBATION-DEPENDENT INHIBITION OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 2B1.European Journal of Pharmaceutical Sciences.2024: 106852.
References
– Lin TI, et al. In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.Antimicrob Agents Chemother. 2009 Apr;53(4):1377-85. Epub 2009 Jan 26.
CAS Number
– 923604-59-5
Molecular Weight
– C38H47N5O7S2
Compound Purity
– 0.9977
SMILES
– COc1ccc2c(O[C@@H]3C[C@@H]4[C@@H](C3)C(=O)N(C)CCCCC=C/[C@@H]3C[C@]3(NC4=O)C(=O)NS(=O)(=O)C3CC3)cc(nc2c1C)-c1nc(cs1)C(C)C
Pathway
– Proteases/Proteasome|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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