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Products Details
Product Description
– SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM). SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases[1].
Web ID
– HY-130631
Shipping
– Room temperature
Molecular Formula
– C12H8O6
References
– [1]Kim B, et al. Development and structure-activity relationship study of SHP2 inhibitor containing 3, 4, 6-trihydroxy-5-oxo-5H-benzo [7] annulene[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30(1): 126756.. . .
CAS Number
– 54755-93-0
Molecular Weight
– 248.19
SMILES
– OC1=CC=C(C=C(C(O)=O)C=C(O)C2=O)C2=C1O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– SHP2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
