SEW​2871

SKU T2171-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,029 CAD

Products Details

Product Description

– SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer’s disease, liver fibrosis, and inflammation. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.

Web ID

– T2171

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H10F6N2OS

References

– Ni Q, et al. Int Immunopharmacol. 2015 May;26(1):37-42.

CAS Number

– 256414-75-2

Molecular Weight

– C20H10F6N2OS

Compound Purity

– 0.9996

SMILES

– FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1cccc(c1)C(F)(F)F

Target

– Wnt/beta-catenin

Pathway

– GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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