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Serlopitant
SKU
HY-12114-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, Neurokinin Receptor, Neurological Disease; Endocrinology
Products Details
Product Description
– Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.
Web ID
– HY-12114
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C29H28F7NO2
References
– [1]Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. J Am Acad Dermatol. 2018 May;78(5):882-891.
CAS Number
– 860642-69-9
Molecular Weight
– 555.53
SMILES
– O=C1C=C(N2C[C@@]3([H])CC[C@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[C@@H](C5=CC=C(F)C=C5)[C@]3([H])C2)CC1
Clinical Information
– Phase 3
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.