Products Details

Product Description

– Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.

Web ID

– HY-12114

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C29H28F7NO2

References

– [1]Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. J Am Acad Dermatol. 2018 May;78(5):882-891.

CAS Number

– 860642-69-9

Molecular Weight

– 555.53

SMILES

– O=C1C=C(N2C[C@@]3([H])CC[C@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[C@@H](C5=CC=C(F)C=C5)[C@]3([H])C2)CC1

Clinical Information

– Phase 3

Research Area

– Neurological Disease; Endocrinology

Solubility

– 10 mM in DMSO

Target

– Neurokinin Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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