Download Files:
Serabelisib
$108 – $660
Products Details
Product Description
– Serabelisib (MLN1117) is a selective p110α inhibitor with an IC50 of 15 nM.
Web ID
– HY-12285
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H17N5O3
References
– [1]So L, et al. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function. J Biol Chem. 2013 Feb 22;288(8):5718-31.
CAS Number
– 1268454-23-4
Molecular Weight
– 363.37
Compound Purity
– 99.21
SMILES
– O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 6.4 mg/mL (ultrasonic;warming)
Target
– PI3K
Isoform
– PI3Kα;PI3Kβ;PI3Kγ;PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
