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Products Details
Product Description
– SEN177 shows the potential in the research of Huntington’s disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].
Web ID
– T61063
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H19FN6
CAS Number
– 2117405-13-5
Molecular Weight
– C18H19FN6
SMILES
– Cn1cnnc1C1CCN(CC1)c1ncccc1-c1ccc(F)nc1
Pathway
– Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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