Download Files:
Selgantolimod
SKU
HY-109137-10 mg
Category Reference compound
Tags Anti-infection;Immunology/Inflammation, HBV;Toll-like Receptor (TLR), Infection
$550 – $4,100
Products Details
Product Description
– Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection[1][2][3].
Web ID
– HY-109137
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H20FN5O
References
– [1]Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.|[2]Benjamin Ryan. Selgantolimod Shows Promise as Treatment for Hepatitis B. November 18, 2019.|[3]Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment of hiv. US20170071944A1.
CAS Number
– 2004677-13-6
Molecular Weight
– 293.34
Compound Purity
– 98.23
SMILES
– C[C@@](CCCC)(CO)NC1=NC(N)=NC2=C1N=CC(F)=C2
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– HBV;Toll-like Receptor (TLR)
Isoform
– TLR8
Pathway
– Anti-infection;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.