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Products Details
Product Description
– sEH inhibitor-3 (compound 35) is a potent and orally active soluble epoxide hydrolase (sEH) inhibitor with a Ki of 0.75 nM for human sEH[1].
Web ID
– HY-146643
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H23F4N3O4
References
– [1]Kin Sing Stephen Lee, et al. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 Nov 15;28(22):115735.
CAS Number
– 1809885-35-5
Molecular Weight
– 433.40
SMILES
– O=C(NC1CCN(CC1)C(C2CCOCC2)=O)NC3=CC=C(C(F)=C3)OC(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Epoxide Hydrolase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
