SCFSkp2-IN-2

SKU T72043-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 525 CAD

Products Details

Product Description

– SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM. It demonstrates antitumor activities by inducing apoptosis in non-small cell lung cancer (NSCLC) cells.

Web ID

– T72043

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H20N4O2

References

– Liu J, et al. Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence. Pharmacol Res. 2022;181:106259.

CAS Number

– 1375060-02-8

Molecular Weight

– C17H20N4O2

Compound Purity

– 0.9928

SMILES

– N(CC)(CC)C1=CC(O)=C(/C=N/NC(=O)C=2C=CC=NC2)C=C1

Pathway

– Ubiquitination|||Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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