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SBI-0206965
Price range: 61 CAD through 717 CAD
Products Details
Product Description
– SBI-0206965 is a potent, selective, and cell-permeable autophagy kinase ULK1 inhibitor with an IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
Web ID
– T2128
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H21BrN4O5
Citations
– 1. Zhang H, Cui Z, Cheng D, et al. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis. Autophagy. 2021 Oct;17(10):3030-3047
2. Qiu W Q, Pan R, Tang Y, et al. Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction. Biomedicine & Pharmacotherapy. 2020, 130: 110575.
References
– Elokdah H, et al. J Med Chem. 2004, 47(14), 3491-3494.
CAS Number
– 1884220-36-3
Molecular Weight
– C21H21BrN4O5
Compound Purity
– 0.9913
SMILES
– CNC(=O)c1ccccc1Oc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Br
Pathway
– Autophagy|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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