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Products Details
Product Description
– SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties[1].
Web ID
– HY-105896
Shipping
– Room temperature
Molecular Formula
– C18H21Cl2N3O4S
References
– [1]Warren D Hirst, et al. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol. 2006 Dec 28;553(1-3):109-19.
CAS Number
– 402713-80-8
Molecular Weight
– 446.35
SMILES
– COC1=C(N2CCNCC2)C=C(S(NC3=C(C(Cl)=CC(Cl)=C3)OC)(=O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Isoform
– 5-HT6 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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