SB228357
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SB228357

SKU T16856-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 858 CAD

Products Details

Product Description

– SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.

Web ID

– T16856

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H17F4N3O2

References

– Bromidge SM, et al. Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent. J Med Chem. 2000 Mar 23;43(6):1123-34.

CAS Number

– 181629-93-6

Molecular Weight

– C22H17F4N3O2

Compound Purity

– 0.9931

SMILES

– COc1cc2CCN(C(=O)Nc3cc(F)cc(c3)-c3cccnc3)c2cc1C(F)(F)F

Target

– Gamma-secretase|||Beta Amyloid|||Microtubule Associated

Pathway

– Neuroscience|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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