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SB 204741
$100 – $590
Products Details
Product Description
– SB 204741 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1[1].
Web ID
– HY-103153
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H14N4OS
References
– [1]Bharti S, et al. 5-HT2B receptor blockade attenuates β-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs. Apoptosis. 2015;20(4):455-465.|[2]Bonhaus DW, et al. The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors. Br J Pharmacol. 1995;115(4):622-628.
CAS Number
– 152239-46-8
Molecular Weight
– 286.35
Compound Purity
– 99.91
SMILES
– O=C(NC1=CC(C)=NS1)NC2=CC3=C(N(C)C=C3)C=C2
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– 5-HT Receptor
Isoform
– 5-HT2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
