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Products Details
Product Description
– SARS-CoV-2 Mpro-IN-6 is a covalent, irreversible and selective SARS-CoV-2 Mpro inhibitor with an IC50 of 0.18 μM. SARS-CoV-2 Mpro-IN-6 does not inhibit human cathepsins B, F, K, and L, and caspase 3[1].
Web ID
– HY-152108
Shipping
– Room temperature
Molecular Formula
– C18H18Cl3N3O2S
References
– [1]Shenghua Gao, et al. Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 Dec 22;65(24):16902-16917.
CAS Number
– 2768834-48-4
Molecular Weight
– 446.78
SMILES
– O=C([C@H]1N(C2=CC=C(Cl)C(Cl)=C2)CCN(C(CCl)=O)C1)NCC3=CC=CS3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
