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Sar-[D-Phe8]-des-Arg9-Bradykinin

Products Details

Product Description

– Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].

Web ID

– HY-103291

Shipping

– Room temperature

Molecular Formula

– C47H66N12O11

References

– [1]Levesque L, et al. Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta. Br J Pharmacol. 1995 Sep;116(1):1673-9.

CAS Number

– 126959-88-4

Molecular Weight

– 975.10

SMILES

– O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC(CNC)=O)=O)N2[C@@H](CCC2)C(NCC(N[C@H](C(N[C@@H](CO)C(N3[C@@H](CCC3)C(N[C@@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)=O)=O

Clinical Information

– No Development Reported

Research Area

– Endocrinology; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Bradykinin Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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