Download Files:
Sapitinib
Price range: 51 CAD through 403 CAD
Products Details
Product Description
– Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the ErbB family over MNK1 and Flt.
Web ID
– T6092
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H25ClFN5O3
Citations
– 1. Machine learning–enabled virtual screening indicates the anti-tuberculosis activity of aldoxorubicin and quarfloxin with verification by molecular docking, molecular dynamics simulations, and biological evaluations
References
– Hickinson DM, et al. Clin Cancer Res, 2010, 16(4), 1159-1169.
CAS Number
– 848942-61-0
Molecular Weight
– C23H25ClFN5O3
Compound Purity
– 0.9889
SMILES
– CNC(=O)CN1CCC(CC1)Oc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
