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Products Details
Product Description
– Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p
Web ID
– HY-N2602
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H26O6
References
– [1]Won YS, Seo KI. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells. Nutrients. 2020;12(2):488. Published 2020 Feb 14.|[2]Won YS, Seo KI. Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor. Food Chem Toxicol. 2020;138:111221.
CAS Number
– 329319-20-2
Molecular Weight
– 422.47
SMILES
– O=C1C2=C(O)C=C3C(C=CC(CC/C=C(C)/C)(C)O3)=C2OC(C4=CC=C(O)C=C4O)C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Natural Products
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