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Salubrinal
Price range: 56 CAD through 1,744 CAD
Products Details
Product Description
– Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).
Web ID
– T3045
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H17Cl3N4OS
Citations
– 1. Meng C, Zhang J, Dang B, et al. PERK pathway activation promotes intracerebral hemorrhage induced secondary brain injury by inducing neuronal apoptosis both in vivo and in vitro. Frontiers in Neuroscience. 2018 Feb 28;12:111
2. Zhao Y, Feng Y, Ye Q, et al.The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.Frontiers in Cellular and Infection Microbiology.2022
3. Berthier A, Gheeraert C, Johanns M, et al.The Molecular Circadian Clock Is a Target of Anti-cancer Translation Inhibitors.Journal of Biological Rhythms.2023: 07487304231202561.
References
– Boyce M, et al. Science, 2005, 307(5711), 935-939.
CAS Number
– 405060-95-9
Molecular Weight
– C21H17Cl3N4OS
Compound Purity
– 0.9997
SMILES
– ClC(Cl)(Cl)C(NC(=S)NC1=CC=CC2=CC=CN=C12)NC(=O)C=CC1=CC=CC=C1
Pathway
– Apoptosis|||Metabolism|||Autophagy|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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