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Salicylic acid
$40 – $90
Products Details
Product Description
– Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
Web ID
– HY-B0167
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C7H6O3
Citations
– Biopharm Drug Dispos. 2022 Oct 4.|bioRxiv. 2023 Jun 3.|Food Chem. 2022: 134807.|Katedra farmakologie a toxikologie. 2020 Jul.|Plant Cell. 2022 Aug 16;koac255.|Cancer Lett. 2021 Jan 1;496:127-133.
References
– [1]Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12.|[2]Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6.
CAS Number
– 69-72-7
Molecular Weight
– 138.12
Compound Purity
– 98.0
SMILES
– O=C(O)C1=CC=CC=C1O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 1 mg/mL (ultrasonic)
Target
– Apoptosis;Autophagy;COX;Endogenous Metabolite;Mitophagy
Isoform
– COX-2;Microbial Metabolite
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
