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Saikosaponin A
$44 – $935
Products Details
Product Description
– Saikosaponin A is an active component of Bupleurum chinensis, up-regulates LXRα expression, with potent anti-inflammatory activity[1].
Web ID
– HY-N0246
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C42H68O13
References
– [1]Jawad Ali, et al. Mucoprotective effects of Saikosaponin-A in 5-fluorouracil-induced intestinal mucositis in mice model. Life Sci. 2019.|[2]Gao H, et al. Saikosaponin A inhibits IL-1β-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXRα. Oncotarget. 2017 Sep 30;8(51):88941-88950.
CAS Number
– 20736-09-8
Molecular Weight
– 780.98
Compound Purity
– 98.53
SMILES
– OC[C@H]1O[C@](O[C@@H]2[C@@H](O)[C@@](O[C@@H]3[C@@](C)(CO)[C@@](CC[C@]4(C)[C@]5([H])C=C[C@@]6(OC7)[C@@]4(C)C[C@H](O)[C@]87[C@@]6([H])CC(C)(C)CC8)([H])[C@]5(C)CC3)([H])O[C@H](C)[C@@H]2O)([H])[C@H](O)[C@@H](O)[C@@H]1O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Bacterial;LXR
Pathway
– Anti-infection;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
