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SAG
Price range: 45 USD through 796 USD
Products Details
Product Description
– SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
Web ID
– T1779
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H28ClN3OS
Citations
– 1. Schenke M, Schjeide B M, Püschel G P, et al. Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays. Toxins. 2020, 12(5): 276
2. Yang Y, Suo N, Cui S, et al.Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation.Acta Pharmacologica Sinica.2024: 1-13.
References
– Xu H, et al. Directed Differentiation of V3 Interneurons from Mouse Embryonic Stem Cells. Stem Cells Dev. 2015 Nov 15;24(22):2723-32.
CAS Number
– 912545-86-9
Molecular Weight
– C28H28ClN3OS
Compound Purity
– 0.9888
SMILES
– CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl
Target
– Others
Pathway
– Stem Cells|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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