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Sabcomeline (hydrochloride)
SKU
HY-106432A-1 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
$200 – $4,200
Products Details
Product Description
– Sabcomeline (SB-202026) hydrochloride is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline hydrochloride can be used for Alzheimer’s disease research[1][2].
Web ID
– HY-106432A
Storage Temperature
– 4°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H16ClN3O
References
– [1]Hosoi R, Kobayashi K, Ishida J, Yamaguchi M, Inoue O. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. |[2]Hatcher JP, Loudon JM, Hagan JJ, Clark MS. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282.
CAS Number
– 159912-58-0
Molecular Weight
– 229.71
Compound Purity
– 99.86
SMILES
– CO/N=C([C@@H]1C2CCN(CC2)C1)C#N.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 125 mg/mL (ultrasonic)
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.