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S49076
$50 – $580
Products Details
Product Description
– S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
Web ID
– HY-12965
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H22N4O4S
References
– [1]Burbridge MF, et al. S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. Mol Cancer Ther. 2013 Sep;12(9):1749-62.
CAS Number
– 1265965-22-7
Molecular Weight
– 438.50
Compound Purity
– 99.71
SMILES
– O=C(N1CC2=CC3=C(NC(/C3=CC4=CC(CN5CCOCC5)=CN4)=O)C=C2)SCC1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 31 mg/mL
Target
– c-Met/HGFR;FGFR
Isoform
– FGFR1;FGFR2;FGFR3
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
