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Products Details
Product Description
– (S)-Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S)-Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].
Web ID
– T84742
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H29ClN4O2
CAS Number
– 1781828-85-0
Molecular Weight
– C28H29ClN4O2
SMILES
– O=C1C(C2=C3N(C=4C2=CC=CC4)CC[C@H](CN(C)C)C3)=C(C(=O)N1)C=5C=6C(N(C)C5)=CC=CC6.Cl
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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