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Products Details
Product Description
– S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor[2].
Web ID
– HY-115754
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H16N2O2S2
References
– [1]Conaway CC, et al. Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes. Chem Res Toxicol. 2001 Sep;14(9):1170-6.|[2]Adesida A, Edwards LG, Thornalley PJ. Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate. Food Chem Toxicol. 1996 Apr;34(4):385-92.
CAS Number
– 53330-02-2
Molecular Weight
– 284.40
SMILES
– N[C@@H](CSC(NCCC1=CC=CC=C1)=S)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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