S-methyl DM1
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S-methyl DM1

SKU T12805-25 mg Category Brand:

Price range: 2,672 CAD through 4,480 CAD

Products Details

Product Description

– S-methyl DM1, a thiomethyl derivative of Maytansine, binds to tubulin (Kd of 0.93 μM) and inhibits microtubule polymerization.

Web ID

– T12805

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H50ClN3O10S

References

– Lopus M, et al. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules. Mol Cancer Ther. 2010 Oct;9(10):2689-99.

CAS Number

– 912569-84-7

Molecular Weight

– C36H50ClN3O10S

SMILES

– C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

Target

– DNA/RNA Synthesis|||p53

Pathway

– Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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