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Products Details
Product Description
– S-Gem is a TrxR-dependent prodrug of Gemcitabine (HY-17026) and selectively activated by TrxR. S-Gem shows less cytotoxicity compared to Gemcitabine[1].
Web ID
– HY-154842
Shipping
– Room temperature
Molecular Formula
– C13H15F2N3O6S2
References
– [1]Li X, et, al. Combination of chemotherapy and oxidative stress to enhance cancer cell apoptosis. Chem Sci. 2020 Feb 25;11(12):3215-3222.
CAS Number
– 2169925-98-6
Molecular Weight
– 411.40
SMILES
– FC1([C@H](N2C(N=C(C=C2)NC(OC3CSSC3)=O)=O)O[C@@H]([C@H]1O)CO)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy;DNA/RNA Synthesis;Nucleoside Antimetabolite/Analog
Pathway
– Apoptosis;Autophagy;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
