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(S)-AMG-510
Price range: 50 CAD through 1,579 CAD
Products Details
Product Description
– (S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C through covalent interaction with mutant cysteine, thereby promoting clinical efficacy in KRASG12C tumors.
Web ID
– T22258
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H30F2N6O3
References
– Canon J , Rex K , Saiki A Y , et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity[J]. Nature, 2019, 575(7781).
CAS Number
– 2252403-56-6
Molecular Weight
– C30H30F2N6O3
Compound Purity
– 0.9976
SMILES
– O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C
Target
– ADC Linker
Pathway
– MAPK|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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