RUNX1/ETO tetramerization-IN-1

SKU T61098-2 mg Category Brand:

Price range: 539 CAD through 4,000 CAD

Products Details

Product Description

– RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor targeting NHR2 of RUNX1/ETO, effectively inhibiting tetramerization with an EC50 value of 0.25 μM. This compound restores gene expression down-regulated by RUNX1/ETO and demonstrates anti-leukemic activity by inhibiting proliferation of RUNX1/ETO-dependent SKNO-1 cells and reducing tumor growth in a mouse model [1] [2] [3].

Web ID

– T61098

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H14O7

CAS Number

– 88755-39-9

Molecular Weight

– C18H14O7

SMILES

– C(CC(=O)C=1C=C2C(=CC1)OCO2)(C(O)=O)C=3C=C4C(=CC3)OCO4

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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