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Rucaparib
Price range: 66 CAD through 1,464 CAD
Products Details
Product Description
– Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC).
Web ID
– T4463
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H18FN3O
Citations
– 1. Lodovichi S, Nepomuceno T C, Woods N T, et al.SART1 modulates Poly-(ADP-Ribose) chain accumulation and PARP1 chromatin localization.iScience.2024
References
– Thomas HD,etal.Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.Mol Cancer Ther. 2007 Mar;6(3):945-56.
CAS Number
– 283173-50-2
Molecular Weight
– C19H18FN3O
Compound Purity
– 0.9989
SMILES
– O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1
Pathway
– DNA Damage/DNA Repair|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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