Rucaparib
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Rucaparib

SKU T4463-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 1,464 CAD

Products Details

Product Description

– Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC).

Web ID

– T4463

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H18FN3O

Citations

– 1. Lodovichi S, Nepomuceno T C, Woods N T, et al.SART1 modulates Poly-(ADP-Ribose) chain accumulation and PARP1 chromatin localization.iScience.2024

References

– Thomas HD,etal.Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.Mol Cancer Ther. 2007 Mar;6(3):945-56.

CAS Number

– 283173-50-2

Molecular Weight

– C19H18FN3O

Compound Purity

– 0.9989

SMILES

– O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

Pathway

– DNA Damage/DNA Repair|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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