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RU-SKI 43
Price range: 72 CAD through 891 CAD
Products Details
Product Description
– RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
Web ID
– T12797
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H30N2O2S
References
– Petrova E, et al. Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling.Nat Chem Biol. 2013 Apr;9(4):247-9.
CAS Number
– 1043797-53-0
Molecular Weight
– C22H30N2O2S
Compound Purity
– 0.9985
SMILES
– C(OC1=CC(C)=CC=C1)C2C3=C(CCN2C(CNCC(CC)C)=O)SC=C3
Target
– Others
Pathway
– Metabolism|||GPCR/G Protein|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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