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RTI 336
SKU
HY-107055-Get quote
Category Reference compound
Tags Dopamine Transporter, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1].
Web ID
– HY-107055
Shipping
– Room temperature
Molecular Formula
– C24H26Cl2N2O
References
– [1]Haile CN, et al. Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter. Brain Res. 2005 Sep 7;1055(1-2):186-95.
CAS Number
– 204069-50-1
Molecular Weight
– 429.38
SMILES
– CN1[C@H]2[C@@H](C3=CC(C4=CC=C(C)C=C4)=NO3)[C@@H](C5=CC=C(Cl)C=C5)C[C@@H]1CC2.Cl
Clinical Information
– Phase 1
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Transporter
Pathway
– Neuronal Signaling
Product type
– Reference compound
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