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Products Details
Product Description
– RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase. RSK2-IN-2 is also described to inhibit MSK1, MSK2 and RSK3[1].
Web ID
– HY-150643
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H11N5O
References
– [1]Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108.
CAS Number
– 1637749-78-0
Molecular Weight
– 289.29
SMILES
– O=C(N)/C(C#N)=C/C1=CC=CC(C2=C3C(NC=C3)=NC=N2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ribosomal S6 Kinase (RSK)
Isoform
– RSK2;RSK3
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
