Download Files:
Rotundic acid
$80 – $130
Products Details
Product Description
– Rotundic acid, a triterpenoid obtained from Ilex rotunda Thunb., induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].
Web ID
– HY-N2217
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C30H48O5
References
– [1]Roy G, et al. Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways. Front Oncol. 2019 Jun 26;9:545.
CAS Number
– 20137-37-5
Molecular Weight
– 488.70
Compound Purity
– 99.41
SMILES
– C[C@@]1(CO)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Akt;Apoptosis;mTOR;p38 MAPK
Isoform
– mTOR;p38 MAPK
Pathway
– Apoptosis;MAPK/ERK Pathway;PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
