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ROS-generating agent 1
Price range: 50 CAD through 2,048 CAD
Products Details
Product Description
– Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.
Web ID
– T77762
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H15F6NO
References
– Liu X, et al. Tumor killing by a dietary curcumin mono-carbonyl analog that works as a selective ROS generator via TrxR inhibition. Eur J Med Chem. 2023 Mar 15;250:115191.
CAS Number
– 2369030-41-9
Molecular Weight
– C21H15F6NO
Compound Purity
– 0.9967
SMILES
– C(=C1/C(=O)C(=CC2=CC(C(F)(F)F)=CC=C2)CNC1)C3=CC(C(F)(F)F)=CC=C3
Pathway
– Apoptosis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
