RORγt Inverse agonist 3

SKU T12752-25 mg Category Brand:

Price range: 2,912 CAD through 4,960 CAD

Products Details

Product Description

– RORγt Inverse Agonist 3 is a potent, selective, and orally active inverse agonist of RORγ with EC50 values of 0.22 μM for hRORγ and 0.15 μM for RORγt (human IL-17 cells), respectively.

Web ID

– T12752

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H31Cl2N5O4S

References

– Amaudrut J, et al. Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1799-1806.

CAS Number

– 2364429-77-4

Molecular Weight

– C29H31Cl2N5O4S

SMILES

– CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(nc23)C(C)C)-c2cncn2C)c1Cl

Target

– Others

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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