Download Files:
Products Details
Product Description
– RORγt modulator 2 (Compound 21) is a modulator of retinoid-related orphan receptor γt (RORγt) with the IC50 of <50 nM. RORγt modulator 2 can be used for the research of RORyt mediated diseases such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer[1].
Web ID
– HY-142935
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H29ClN2O4S
References
– [1]V. S. Prasada Rao Lingam, et al. Substituted oxoazetidine analogues as ror gamma modulators.
CAS Number
– 2247083-47-0
Molecular Weight
– 525.06
SMILES
– CC([C@@H]1[C@](C2=CC=C(C=C2)Cl)([H])N(C3=CC=C(C=C3)C(NCC4=CC=C(C=C4)S(CC)(=O)=O)=O)C1=O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– ROR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
