Download Files:
Products Details
Product Description
– RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC50 value of 1 nM.
Web ID
– HY-142296
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H21ClFN3O4
References
– [1]Zhang H, et al. Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases. ACS Med Chem Lett. 2020 Jan 9;11(2):114-119.
CAS Number
– 1561770-72-6
Molecular Weight
– 457.88
SMILES
– O=C([C@@H]1CCN(C[C@H]1O)C2=NN(C3=CC=CC(F)=C32)C(C4=C(C=CC=C4Cl)C5CC5)=O)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
![9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin](https://immunomart.com/wp-content/uploads/2024/02/HY-W334680-350x350.gif)
