Roniciclib
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Roniciclib

SKU T16784-1 mg Category Brand:

Price range: 88 CAD through 1,354 CAD

Products Details

Product Description

– Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.

Web ID

– T16784

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H21F3N4O3S

References

– Siemeister G, et al. BAY 1000394, a novel cyclin-dependent kinase inhibitor, with potent antitumor activity in mono- and in combination treatment upon oral application. Mol Cancer Ther. 2012 Oct;11(10):2265-73.

CAS Number

– 1223498-69-8

Molecular Weight

– C18H21F3N4O3S

Compound Purity

– 0.9884

SMILES

– C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F

Target

– Others

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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