Ro 67-7476
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Ro 67-7476

SKU T3478-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 1,144 CAD

Products Details

Product Description

– Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.

Web ID

– T3478

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H18FNO2S

Citations

– 1. Wang J, Wang J, Lu C, et al.ISL1-overexpressing BMSCs attenuate renal ischemia-reperfusion injury by suppressing apoptosis and oxidative stress through the paracrine action.Cellular and Molecular Life Sciences.2024, 81(1): 312.

References

– Hemstapat K et al. A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators. Mol Pharmacol. 2006 Aug, 70(2), 616-26

CAS Number

– 298690-60-5

Molecular Weight

– C17H18FNO2S

Compound Purity

– 0.9948

SMILES

– Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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