RMC-0331
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RMC-0331

SKU T38170-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 237 CAD through 5,056 CAD

Products Details

Product Description

– RMC-0331 (RM-023) is an orally available and potent SOS1 inhibitor with potential anticancer activity, blocking RAS activation by disrupting RAS-SOS1 interactions.

Web ID

– T38170

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H25ClF3N5O3

References

– Buckl A,et al. Discovery of a potent, selective, and orally bioavailable SOS1 inhibitor, RMC-023, an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction[J]. Cancer Research, 2021, 81(13_Supplement): 1273-1273.

CAS Number

– 2488788-52-7

Molecular Weight

– C22H25ClF3N5O3

Compound Purity

– 0.9981

SMILES

– COC1(CCOCC1)C(=O)N1Cc2nc(Cl)nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2C1

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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