Ritlecitinib

SKU T5382-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 1,792 CAD

Products Details

Product Description

– Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor with an IC50 of 33.1 nM and does not affect the activity of JAK1/2.

Web ID

– T5382

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H19N5O

References

– Telliez JB, et al. Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. ACS Chem Biol. 2016 Dec 16;11(12):3442-3451.

CAS Number

– 1792180-81-4

Molecular Weight

– C15H19N5O

Compound Purity

– 0.9892

SMILES

– C[C@H]1CC[C@H](CN1C(=O)C=C)Nc1ncnc2[nH]ccc12

Pathway

– Stem Cells|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Angiogenesis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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