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Products Details
Product Description
– RIP1 kinase inhibitor 7 (compound 41) is a potent receptor interacting protein 1 kinase (RIP1) Inhibitor with an IC50 of <100 nM for human RIP1. RIP1 kinase inhibitor 7 has an EC50 of 1-100 nM in the cell necrosis assay[1].
Web ID
– HY-153437
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H20FN3O
References
– [1]Yaning SU, et al. Cyclic Ureas. WO2020103884A1.
CAS Number
– 2428401-23-2
Molecular Weight
– 337.39
SMILES
– O=C(N1CC(C1)CC2=CC(F)=CC=C2)N3N=CCC3C4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RIP kinase
Isoform
– RIPK1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
