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RIG012
$350 – $1,250
Products Details
Product Description
– RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression[1].
Web ID
– HY-147124
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C23H21NO3
References
– [1]David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317.
CAS Number
– 2642218-43-5
Molecular Weight
– 359.42
Compound Purity
– 99.0
SMILES
– O=C1N=C2C3=C(C(C(OCC4=CC=CC=C4)=C2C1(CC)CC)=O)C=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– IFNAR
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
