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Ribociclib succinate
Price range: 48 CAD through 814 CAD
Products Details
Product Description
– Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.
Web ID
– T15732
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H36N8O5
Citations
– 1. Crystal structure of ribociclib hydrogen succinate, (C23H31N8O)(HC4H4O4)
References
– VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.
CAS Number
– 1374639-75-4
Molecular Weight
– C27H36N8O5
Compound Purity
– 0.999
SMILES
– OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1
Target
– EGFR
Pathway
– Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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