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RI-2
$200 – $1,650
Products Details
Product Description
– RI-2 is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM, and specifically inhibits homologous recombination repair in human cells.
Web ID
– HY-16904
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H18Cl2N2O4
References
– [1]Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63.
CAS Number
– 1417162-36-7
Molecular Weight
– 433.28
Compound Purity
– 99.64
SMILES
– O=C(C(C1=CC=C(OC)C=C1)=C2N3CCOCC3)N(C4=CC=C(Cl)C(Cl)=C4)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 130 mg/mL (ultrasonic)
Target
– RAD51
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
