RGB-286638 free base

SKU T2378-1 mg Category Brand:

Price range: 62 CAD through 939 CAD

Products Details

Product Description

– RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.

Web ID

– T2378

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H35N7O4

References

– Cirstea D, et al. Leukemia. 2013 Dec;27(12):2366-75.

CAS Number

– 784210-88-4

Molecular Weight

– C29H35N7O4

Compound Purity

– 0.9991

SMILES

– COCCN1CCN(Cc2ccc(cc2)-c2n[nH]c3-c4cccc(NC(=O)NN5CCOCC5)c4C(=O)c23)CC1

Pathway

– Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Angiogenesis|||MAPK|||Chromatin/Epigenetic|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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