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Reveromycin A
$2,150
Only 1000 item(s) left in stock.
Products Details
Product Description
– Reveromycin A, a benzoquinoid antibiotic isolated from the genus Streptomyces, is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity[1][2].
Web ID
– HY-129337
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C36H52O11
References
– [1]H Takahashi , et al. Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. J Antibiot (Tokyo). 1992 Sep;45(9):1414-9.|[2]Je-Tae Woo, et al. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4729-34.
CAS Number
– 134615-37-5
Molecular Weight
– 660.79
Compound Purity
– 99.0
SMILES
– O=C(O[C@@]1(CCCC)[C@H](/C=C/C(C)=C/C(O)=O)O[C@]2(O[C@H](C/C=C(C)/C=C/[C@H](O)[C@@H](C)/C=C/C(O)=O)[C@@H](C)CC2)CC1)CCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Fungal
Pathway
– Anti-infection;Apoptosis
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
