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Retagliptin

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Products Details

Product Description

– Retagliptin (SP2086) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin can be used for type 2 diabetes mellitus (T2DM) research[1].

Web ID

– HY-112668A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C19H18F6N4O3

References

– [1]Avivit Cahn, et al. An update on DPP-4 inhibitors in the management of type 2 diabetes. Expert Opin Emerg Drugs. 2016 Dec;21(4):409-419.

CAS Number

– 1174122-54-3

Molecular Weight

– 464.36

Compound Purity

– 99.70

SMILES

– O=C(C1=C2CN(C(C[C@H](N)CC3=CC(F)=C(F)C=C3F)=O)CCN2C(C(F)(F)F)=N1)OC

Clinical Information

– Phase 3

Research Area

– Metabolic Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Dipeptidyl Peptidase

Isoform

– DPP-4

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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